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These selected publications highlight the major themes of research at Mercy Perinatal. Further information on individual researchers and Obstetrics and Gynaecology Research at the University of Melbourne can be found here.

Using the methylome to predict pre-eclampsia

Kaitu'u-Lino TJ, Bartho LA, Tong S. Nat Med. 2023 Sep;29(9):2177-2178. doi: 10.1038/s41591-023-02499-x. PMID: 3764085...
Consumer Insights from a Feasibility Study on Remote and Extended Use of a Novel Non-Invasive Wearable Fetal Electrocardiogram Monitor

Karmarkar D, Emerson Keenan, Brownfoot F. Nature Digital Medicine. Accepted for publication 9th April 2025
Rapid detection of fetal compromise using input length invariant deep learning on fetal heart rate signals

Mendis L, Palaniswami M, Keenan E, Brownfoot F. Sci Rep 14, 12615 (2024). https://doi.org/10.1038/s41598-024-63108-6
Metformin as a prevention and treatment for preeclampsia: effects on soluble fms-like tyrosine kinase 1 and soluble endoglin secretion and endothelial dysfunction

Brownfoot FC, Hastie R, Hannan NJ, Cannon P, Tuohey L, Parry LJ, Senadheera S, Illanes SE, Kaitu’u-Lino, TJ, Tong S. Am...
Use of Metformin to prolong gestation in preterm pre-eclampsia: randomised, double blind placebo controlled trial

Cluver CA, Hiscock R, Decloedt EH, Hall DR, Schell S, Mol BW, Brownfoot F, Kaitu’u-Lino TJ, Walker SP, Tong S. BMJ 20...
Sulfasalazine reduces placental secretion of antiangiogenic factors, up-regulates the secretion of placental growth factor and rescues endothelial dysfunction

Brownfoot FC, Hannan NJ, Cannon P, Nguyen V, Hastie R, Parry LJ, Senadheera S, Tuohey L, Tong S, Kaitu'u-Lino TJ. EB...
An estriol-eluting pessary to treat pelvic organ prolapse

Long J, Zidan G, Seyfoddin A, Tong S, Brownfoot FC, Chowdary P. Sci Rep. 2022 Nov 21;12(1):20021. doi: 10.1038/s41598-...
Different corticosteroids and regimens for accelerating fetal lung maturation for women at risk of preterm birth

Brownfoot FC, Gagliardi DI, Bain E, Middleton P, Crowther CA. Cochrane Database Syst Rev. 2013 Aug 29;(8):CD006764. ...
Circulating SPINT1 is a biomarker of pregnancies with poor placental function and fetal growth restriction

Kaitu'u-Lino TJ, MacDonald TM, Cannon P, Nguyen TV, Hiscock RJ, Haan N, Myers JE, Hastie R, Dane KM, Middleton AL, Bitta...
Circulating serine peptidase inhibitor Kunitz type 1 (SPINT1) in the second trimester is reduced among pregnancies that end in low birthweight neonates: cohort study of 2006 pregnancies

Tong S, Walker SP, Keenan E, MacDonald TM, Taylor R, McCowan LME, Kaitu'u-Lino TJ. Am J Obstet Gynecol MFM. 2022 Jul;4(...

Using the methylome to predict pre-eclampsia

Consumer Insights from a Feasibility Study on Remote and Extended Use of a Novel Non-Invasive Wearable Fetal Electrocardiogram Monitor

Rapid detection of fetal compromise using input length invariant deep learning on fetal heart rate signals

Metformin as a prevention and treatment for preeclampsia: effects on soluble fms-like tyrosine kinase 1 and soluble endoglin secretion and endothelial dysfunction

Use of Metformin to prolong gestation in preterm pre-eclampsia: randomised, double blind placebo controlled trial

Sulfasalazine reduces placental secretion of antiangiogenic factors, up-regulates the secretion of placental growth factor and rescues endothelial dysfunction

An estriol-eluting pessary to treat pelvic organ prolapse

Different corticosteroids and regimens for accelerating fetal lung maturation for women at risk of preterm birth

Circulating SPINT1 is a biomarker of pregnancies with poor placental function and fetal growth restriction

Circulating serine peptidase inhibitor Kunitz type 1 (SPINT1) in the second trimester is reduced among pregnancies that end in low birthweight neonates: cohort study of 2006 pregnancies

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